The Health Benefits of Curcumin
The health benefits of Curcumin include potent anti-inflammatory effects, anti-cancer properties, alleviation of cognitive decline associated with ageing, and it reduces the risk of diabetes. Many hundreds of studies have indicated significant evidence of its potential against several chronic diseases. In fact, curcumin has shown beneficial effects against several types of cancers, and research has shown that it has even reduced the severity of radiation dermatitis in breast cancer patients.
What is Curcumin?
Curcumin or diferuloylmethane is a yellow polyphenolic compound and the active ingredient in the golden spice turmeric (Curcuma longa) and is also present in limited amounts in ginger. Curcumin is both a powerful anti-inflammatory and a potent antioxidant. The curcumin content of turmeric is relatively low, in the region of about 3-5% by weight.
Despite the impressive health benefits of curcumin, some of the significant problems with curcumin supplements according to studies include poor absorption, metabolism and bioavailability. Research, however, has revealed means of overcoming these problems.
Coyne Healthcare Bio-Curcumin, for example, utilises BCM-95 in its supplement. BCM-95 has been scientifically proven to be a highly efficient and effective way to supplement with Curcumin.
A Pilot Cross-Over Study to Evaluate Human Oral Bioavailability of BCM-95… View Research Paper
There is an urgent need to find ways and means to enhance the bioabsorbability of curcumin so that its potential beneficial effects can be realized clinically. Results of the present study indicate that the proprietary formulation BCM-95®CG (Biocurcumax™) largely meets such a demand.
Lipolife Liposomal Curcumin uses liposomal encapsulation to improve bioavailability. A liposome is a nano-sized sphere or vesicle made from a phospholipid called phosphatidylcholine, which is the same substance found in our cell membranes. Liposomal encapsulation is a process that fills these bubbles with curcumin to provide a very effective method of bypassing the destructive elements of the gastric system and aiding the encapsulated nutrient to be delivered to the cells and tissues.
Recent Developments in Delivery, Bioavailability, Absorption and Metabolism of Curcumin View Research Paper
In rat oral administration of liposome-encapsulated curcumin (LEC) showed high bioavailability of curcumin. In addition, a faster rate and better absorption of curcumin were observed as compared to the other forms.
Curcumin as an Arthritis Treatment
Curcumin reduces the pain, inflammation and stiffness related to rheumatoid arthritis and osteoarthritis. Traditionally Turmeric has been used in Chinese and Indian Ayurvedic medicine to treat arthritis. Curcumin blocks inflammatory cytokines and enzymes, including cyclooxygenase-2, the target of the active ingredient of a leading anti-inflammatory drug. Some recent studies have shown that curcumin has anti-inflammatory properties and modifies immune system responses.
A 2010 clinical trial found that a turmeric supplement standardised to 75 percent curcumin combined with phosphatidylcholine (liposomal encapsulation) provided long-term improvement in pain and function in 100 patients with knee Osteoarthritis.
A 2012 study found that a curcumin-based product utilising BCM-95 reduced joint pain and swelling in patients with active Rheumatoid Arthritis better than a leading nonsteroidal anti-inflammatory drug (NSAID).
A Randomized, Pilot Study to Assess the Efficacy and Safety of Curcumin in Patients with Active Rheumatoid Arthritis: View Research Paper
Our study provides the first evidence for the safety and superiority of curcumin treatment in patients with active RA, and highlights the need for future large-scale trials to validate these findings in patients with RA and other arthritic conditions.
Efficacy of Turmeric Extracts and Curcumin for Alleviating the Symptoms of Joint Arthritis: View Research Paper
This systematic review and meta-analysis provided scientific evidence that 8–12 weeks of standardized turmeric extracts (typically 1000 mg/day of curcumin) treatment can reduce arthritis symptoms (mainly pain and inflammation-related symptoms) and result in similar improvements of the symptoms as ibuprofen and diclofenac sodium.
Curcumin: a new paradigm and therapeutic opportunity for the treatment of osteoarthritis: View Research Paper
The promising in vitro results and the interesting clinical observations gathered here for curcumin should refocus efforts to develop therapies based on new formulations of curcumin.
Curcumin as a Cancer Treatment
Researchers have studied Curcumin extensively for its ability cause the programmed apoptosis of, or its ability to kill, various types of cancer cells. It also has been shown to act as a chemotherapy and radiation-therapy sensitiser, meaning that it helps sensitise the tumours to cancer therapies, in turn making the treatments more effective. Also, curcumin has been shown to protect healthy tissues from the side-effects of these therapies. A phase I clinical trial studied the effects of administering curcumin to 25 patients with precancerous changes in various organs. This study appeared to demonstrate that curcumin could prevent the precancerous changes from becoming cancer.
Liposomal curcumin and its application in cancer View Research Paper
Liposomal CUR formulation has greater growth inhibitory and pro-apoptotic effects on cancer cells.
Therefore, the combination of CUR and liposomes may be an ideal strategy in clinical practice to treat cancers.
Recent Developments in Delivery, Bioavailability, Absorption and Metabolism of Curcumin: View Research Paper
…in vitro and animal studies have shown anticancer activities of curcumin for virtually all types of human cancers…
Curcumin: An Anti-Inflammatory Molecule from a Curry Spice on the Path to Cancer Treatment: View Research Paper
Oxidative damage and inflammation have been pointed out in preclinical studies as the root cause of cancer and other chronic diseases such as diabetes, hypertension, Alzheimer’s disease, etc. Epidemiological and clinical studies have suggested that cancer could be prevented or significantly reduced by treatment with anti-oxidant and anti-inflammatory drugs, therefore, curcumin, a principal component of turmeric (a curry spice) showing strong anti-oxidant and anti-inflammatory activities, might be a potential candidate for the prevention and/or treatment of cancer and other chronic diseases.
Curcumin and Cancer Cells: How Many Ways Can Curry Kill Tumor Cells Selectively?: View Research Paper
Overall, our review shows that curcumin can kill a wide variety of tumor cell types through diverse mechanisms.
Curcumin in combined cancer therapy: View Research Paper
All these facts, tested and confirmed in many different biological systems, have paved the way for research aimed to elucidate the potential beneficial effects of combining curcumin and various anti-cancer drugs in order to establish more efficient and less toxic cancer treatment modalities.
What People are Saying
Bio-Curcumin has drastically reduced the pain of my arthritis, and the swelling is practically gone too.
I was taking two large capsules of another brand of curcumin for my arthritis pain and it was helping but not enough. Within a few days of taking just one, smaller, capsule of Bio-Curcumin per day, my arthritis pain is almost completely gone.
I am delighted. My teeth also feel much healthier, ‘cleaner’ as if plaque formation is reducing and I continue to have no inflammation.
The health benefits of Curcumin are extraordinary and include anti-inflammatory effects, anti-cancer properties, it alleviates cognitive decline, and it also reduces the risk of diabetes. In South Africa, we have a selection of many excellent curcumin supplements.